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The impaired production of LA leads to a disruption in the overall antioxidant defense system, thereby promoting inflammation and dysfunction of the mitochondria [22, 23]
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In advanced fibrotic stages, saponins (e.g., ginsenoside Rg1) and low-dose anthraquinones (e.g., emodin) delay collagen deposition by modulating the gut-liver axis and suppressing TGF-1/Smad3 signaling (Yang et al., 2022)
Acupuncture is a very effective treatment for musculoskeletal disorders including back pain, intervertebral disc problems, muscle soreness, osteoarthritis and degenerative joint disease, and neurological disorders
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